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Select Analysis > Tools > Copy Raster
Select a mosaic dataset in either local or remote database. (e.g., C:\Users\Administrator\Documents\aws_rds_geodb_conn.sde\sdt_db.sdt_user.cer_syn1deg_1hour_terra_aqua_modis)
Select output file name (e.g., c:/tmp/crf/ceres.crf)
In Properties tab, Check Process as Multidimensional.
Check Build Multidimensional Transpose.
In Environment tab, select LERC for compression.
Change Width and Height to match raster x and y size. E.g., 360 and 180 for CERES.
Upload CRF folder into an S3 bucket.
Create S3 connection using Create Cloud Connection tool in Toolbox.
Add it into folder in catalog pane.
Browse the connection using catalog pane.
Select CRF file that you uploaded. Share as web layer in portal as image service.

Info
Abhijit said MDCS is scripting solution for CRF conversion as well.

References